Please use this identifier to cite or link to this item: https://ir.sc.mahidol.ac.th/handle/123456789/825
Title: Screening and discrimination of Hepatocellular carcinoma patients by testing exhaled breath with smart devices using composite polymer/carbon nanotube gas sensors
Authors: Teerakiat Kerdcharoen
Keywords: Electronic nose;Gas sensors;Human exhaled breath;Liver cancer monitoring;VOCs
Issue Date: 2017
Publisher: Institute of Electrical and Electronics Engineers
Citation: Eamsa-Ard T, Seesaard T, Kitiyakara T, Kerdcharoen T. Screening and discrimination of Hepatocellular carcinoma patients by testing exhaled breath with smart devices using composite polymer/carbon nanotube gas sensors. Institute of Electrical and Electronics Engineers Inc.; 2017.
Abstract: There is currently great interest in the medical application of electronic nose and chemical sensors, especially in the area of early diagnosis and screening of diseases. In this study, a pocket electronic nose based on eight nanocomposite gas sensors made of polymer and functionalized single-walled carbon nanotubes (f-SWCNTs) was shown to be capable to discriminate between the two sample groups of hepatocellular carcinoma (HCC) patients and healthy control subjects. Polymer/f-SWCNTs sensor-integrated electronic nose system has been designed and fabricated to be suitable for exhaled breath detection. This chemical gas sensor array has a good sensitivity to a broad range of volatile organic compounds (VOCs), sufficiently to cover the chemical species contained in the human exhaled breath such as acetone, ammonia, methyl-ethyl-ketone, and toluene (excluding water that has negligible impact on sensitivity of the sensors). The obtained results demonstrate that the e-nose has a potential to discriminate the patterns of exhaled breath odor from five healthy controls from five HCC patients, as analyzed by the principal component analysis (PCA) with 95% of the confidence level. In the near future, this approach may become very useful in clinical application to serve as a non-invasive device for screening patients with early-stage liver cancer.
URI: https://ir.sc.mahidol.ac.th/handle/123456789/825
http://ieeexplore.ieee.org/document/7859609/
ISBN: 978-150903940-1
Appears in Collections:Physics: International Proceedings

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